RIZE was created in 2017 with an ambitious mission to end opioid overdose. Guided by those with lived experience and unafraid of new ideas, RIZE invests in community partners who are using novel approaches to prevent overdose and treat addiction, serves as a neutral convenor and network-builder, and funds research that builds the evidence base. Learn how our work has improved the quality of life for people living with substance use disorder.
The number of overdose deaths nationally in 2021, the deadliest year on record
The number of people who die every day in Massachusetts from overdose
Our Areas of Impact
Ending the overdose crisis requires a comprehensive and flexible approach. No one policy or program alone is sufficient to address the magnitude of the crisis. We organize our work into three focus areas:

Investing in Community

Generating Knowledge

Convening for Action
The latest from RIZE
RIZE Massachusetts Funds Project to Validate Accuracy of Xylazine Test Strips
RIZE Massachusetts has awarded a $69,500 Insights and Solutions grant to the Opioid Policy Research Collaborative at Brandeis University and the Massachusetts Drug Supply Data Stream (MADDS) to study and validate the accuracy of xylazine test strips.
RIZE Massachusetts Awards $55,000 to Nonprofits on ‘Frontline’ of Overdose Epidemic
RIZE Massachusetts, an independent nonprofit foundation working to end the overdose epidemic in Massachusetts, today announced that 11 nonprofit organizations have been awarded Frontline Funds to support programming focused on youth and families affected by opioid use disorder.
Learning Community: Harm Reduction. Housing. Hope.
On December 14, 2021, RIZE Massachusetts Foundation, together with the National Harm Reduction Coalition and the Kraft Center for Community Health at MGH hosted a Learning Community: Harm Reduction. Housing. Hope.
Support Our Work
Contributing to RIZE’s growing fund that is dedicated to ending overdose amplifies the power and reach of your donation many times over, helping thousands of people and families across Massachusetts.